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Multiple Choice
Which hormone is synthesized from molecules of the neurotransmitter serotonin in the pineal gland?
A
Cortisol
B
Insulin
C
Epinephrine
D
Melatonin
Verified step by step guidance
1
Understand the role of the pineal gland: The pineal gland is a small endocrine gland in the brain that regulates biological rhythms, including sleep-wake cycles, by producing specific hormones.
Identify the precursor molecule: Serotonin is a neurotransmitter that serves as the precursor for the synthesis of melatonin in the pineal gland.
Learn the synthesis pathway: Serotonin undergoes enzymatic conversion in the pineal gland. First, serotonin is acetylated by the enzyme serotonin N-acetyltransferase to form N-acetylserotonin. Then, N-acetylserotonin is methylated by the enzyme hydroxyindole-O-methyltransferase (HIOMT) to produce melatonin.
Clarify the function of melatonin: Melatonin is a hormone that regulates circadian rhythms and promotes sleep. It is synthesized primarily during the night in response to darkness.
Eliminate incorrect options: Cortisol is produced by the adrenal glands and regulates stress responses. Insulin is produced by the pancreas and regulates blood sugar levels. Epinephrine (adrenaline) is also produced by the adrenal glands and is involved in the fight-or-flight response. None of these are synthesized from serotonin in the pineal gland.