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Multiple Choice
In cell signaling, how are messages relayed and amplified within a cell after a signaling molecule binds to its receptor?
A
By immediate degradation of the signaling molecule, which triggers gene expression
B
Through passive transport of ions across the plasma membrane without any involvement of proteins
C
Through a cascade of intracellular signaling molecules, often involving phosphorylation events that amplify the signal
D
By direct diffusion of the signaling molecule into the nucleus without any intermediate steps
Verified step by step guidance
1
Step 1: Understand the concept of cell signaling. Cell signaling is the process by which cells communicate with each other to coordinate their functions. It typically involves a signaling molecule (ligand) binding to a receptor on the target cell's surface or inside the cell.
Step 2: Recognize the role of the receptor. When a signaling molecule binds to its specific receptor, it triggers a conformational change in the receptor, activating it. This activation initiates the intracellular signaling process.
Step 3: Learn about signal transduction cascades. After receptor activation, the signal is relayed inside the cell through a series of intracellular signaling molecules. These molecules often include proteins, ions, or second messengers like cyclic AMP (cAMP).
Step 4: Understand amplification through phosphorylation. A common mechanism in signal transduction is phosphorylation, where enzymes called kinases add phosphate groups to proteins. This modification activates or deactivates proteins, amplifying the signal as it progresses through the cascade.
Step 5: Recognize the outcome of the signaling cascade. The amplified signal ultimately reaches its target, such as the activation of transcription factors in the nucleus, leading to changes in gene expression or other cellular responses.