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Multiple Choice
Which of the following is a characteristic of an autosomal dominant disorder pedigree?
A
The disorder is only passed from mothers to sons.
B
The disorder skips generations.
C
The disorder appears in every generation.
D
Only males are affected by the disorder.
Verified step by step guidance
1
Understand the concept of autosomal dominant inheritance: In autosomal dominant disorders, only one copy of the mutated gene is needed for an individual to be affected. This means that if a parent has the disorder, there is a 50% chance of passing it to each child.
Examine the pattern of inheritance: Autosomal dominant disorders typically appear in every generation because affected individuals have a 50% chance of passing the disorder to their offspring.
Consider the gender of affected individuals: Autosomal dominant disorders affect both males and females equally, as the gene is located on one of the autosomes (non-sex chromosomes).
Analyze the statement 'The disorder is only passed from mothers to sons': This is incorrect for autosomal dominant disorders, as they are not linked to sex chromosomes and can be passed from either parent to any child.
Evaluate the statement 'The disorder skips generations': This is not characteristic of autosomal dominant disorders, as they usually appear in every generation due to the 50% inheritance chance.