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Multiple Choice
Which molecule is primarily responsible for triggering apoptosis in cell signaling pathways?
A
Cholesterol
B
Glucose
C
Cytochrome c
D
ATP
Verified step by step guidance
1
Understand that apoptosis is a form of programmed cell death, which is a crucial process in development and maintaining the health of an organism.
Recognize that apoptosis is often triggered by signals that lead to the activation of a cascade of proteolytic enzymes called caspases.
Identify that cytochrome c, a component of the electron transport chain in mitochondria, plays a key role in the intrinsic pathway of apoptosis.
Learn that upon receiving apoptotic signals, cytochrome c is released from the mitochondria into the cytosol.
Know that once in the cytosol, cytochrome c binds to Apaf-1 (apoptotic protease activating factor-1), leading to the formation of the apoptosome, which then activates initiator caspases, triggering the apoptotic cascade.