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Multiple Choice
Which immunoglobulin(s) are primarily found on the surface of mature B-cells?
A
IgG only
B
IgE and IgG
C
IgA and IgE
D
IgM and IgD
Verified step by step guidance
1
Understand the role of immunoglobulins (antibodies) in the immune system. Immunoglobulins are proteins produced by B-cells that play a key role in identifying and neutralizing pathogens.
Recall that mature B-cells express specific immunoglobulins on their surface as part of their development and function. These surface immunoglobulins act as receptors for antigens.
Identify the immunoglobulins that are typically expressed on the surface of mature, naive B-cells. These are primarily **IgM** and **IgD**, which serve as antigen receptors.
Eliminate the incorrect options by analyzing the roles of other immunoglobulins: IgG is primarily found in the blood and extracellular fluid, IgE is involved in allergic responses, and IgA is found in mucosal areas.
Conclude that the correct answer is IgM and IgD, as these are the immunoglobulins primarily found on the surface of mature B-cells.