Join thousands of students who trust us to help them ace their exams!Watch the first video
Multiple Choice
Is alkaptonuria caused by a dominant allele or by a recessive allele?
A
Recessive allele
B
Dominant allele
Verified step by step guidance
1
Understand the basic genetics: In genetics, alleles can be dominant or recessive. A dominant allele expresses its trait even if only one copy is present, while a recessive allele requires two copies (one from each parent) to express the trait.
Research alkaptonuria: Alkaptonuria is a rare genetic disorder characterized by the accumulation of homogentisic acid, leading to darkened urine and other symptoms. It is caused by a mutation in the HGD gene.
Identify the inheritance pattern: Alkaptonuria is known to follow an autosomal recessive inheritance pattern. This means that an individual must inherit two copies of the mutated gene (one from each parent) to exhibit symptoms of the disorder.
Analyze the genetic implications: If alkaptonuria were caused by a dominant allele, only one copy of the mutated gene would be necessary for the disorder to manifest. However, since it is recessive, both alleles must be mutated for the condition to appear.
Conclude based on evidence: Given the autosomal recessive inheritance pattern of alkaptonuria, it is caused by a recessive allele. This means that individuals with one normal and one mutated allele (carriers) do not show symptoms of the disorder.