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Multiple Choice
In which phase of mitosis are the duplicated sister chromatids joined together at the centromere?
A
Metaphase
B
Prophase
C
Anaphase
D
Telophase
Verified step by step guidance
1
Understand the process of mitosis, which is the division of a single cell into two genetically identical daughter cells. It consists of several phases: prophase, metaphase, anaphase, and telophase.
Recall that during prophase, the chromatin condenses into visible chromosomes, and each chromosome has already been duplicated into two sister chromatids joined at a region called the centromere.
In metaphase, the chromosomes align at the metaphase plate, which is an imaginary line equidistant from the two centrosome poles. The sister chromatids are still joined together at the centromere during this phase.
During anaphase, the centromeres split, and the sister chromatids are pulled apart toward opposite poles of the cell by the spindle fibers.
In telophase, the separated chromatids, now individual chromosomes, reach the poles of the cell, and the nuclear envelope begins to reform around each set of chromosomes.