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Multiple Choice
Which of the following occurs in eukaryotic translation but not in prokaryotic translation?
A
Initiation with formylmethionine
B
Polycistronic mRNA translation
C
5' cap recognition by ribosome
D
Shine-Dalgarno sequence binding
Verified step by step guidance
1
Understand the basic differences between eukaryotic and prokaryotic translation. Eukaryotic translation occurs in the cytoplasm and involves more complex initiation factors compared to prokaryotic translation.
Recognize that eukaryotic mRNA has a 5' cap structure, which is a modified guanine nucleotide added to the 5' end of the mRNA. This cap is crucial for the initiation of translation in eukaryotes.
Identify that the 5' cap is recognized by the eukaryotic ribosome during the initiation phase of translation. This recognition is facilitated by specific cap-binding proteins.
Contrast this with prokaryotic translation, where the ribosome binds to the mRNA at the Shine-Dalgarno sequence, a purine-rich region upstream of the start codon, without the need for a 5' cap.
Conclude that the recognition of the 5' cap by the ribosome is a unique feature of eukaryotic translation, distinguishing it from prokaryotic translation processes.