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Multiple Choice
Which enzyme reduces the likelihood of DNA loss from telomeres during replication?
A
DNA polymerase III
B
Telomerase
C
Ligase
D
Helicase
Verified step by step guidance
1
Understand the role of telomeres: Telomeres are repetitive DNA sequences at the ends of chromosomes that protect genetic information during replication. However, due to the limitations of DNA polymerase, telomeres shorten with each cell division.
Recognize the problem: DNA polymerase cannot fully replicate the ends of linear DNA, leading to gradual telomere shortening. This can result in the loss of important genetic information over time.
Learn about telomerase: Telomerase is an enzyme that adds repetitive nucleotide sequences to the ends of telomeres, compensating for the shortening that occurs during replication. It helps maintain chromosome integrity and prevents DNA loss.
Compare the options: DNA polymerase III synthesizes new DNA strands but cannot extend telomeres. Ligase joins DNA fragments but does not address telomere shortening. Helicase unwinds DNA but does not prevent telomere loss. Telomerase specifically addresses the issue of telomere shortening.
Conclude: Telomerase is the enzyme responsible for reducing the likelihood of DNA loss from telomeres during replication by adding repetitive sequences to the ends of chromosomes.