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Multiple Choice
How does low-density lipoprotein (LDL) differ from high-density lipoprotein (HDL) in the context of cell signaling and cholesterol transport?
A
LDL is synthesized in the liver, while HDL is synthesized in the intestines only.
B
LDL functions as a hormone receptor, while HDL acts as a second messenger.
C
LDL is primarily composed of proteins, whereas HDL is mainly composed of lipids.
D
LDL delivers cholesterol to cells, while HDL removes excess cholesterol from cells and transports it to the liver.
Verified step by step guidance
1
Understand the role of lipoproteins in cholesterol transport: Lipoproteins are molecules that transport cholesterol and other lipids through the bloodstream. They are essential for maintaining cellular function and overall lipid homeostasis.
Differentiate between LDL and HDL: Low-density lipoprotein (LDL) is often referred to as 'bad cholesterol' because it delivers cholesterol to cells, which can lead to plaque buildup in arteries if levels are too high. High-density lipoprotein (HDL), known as 'good cholesterol,' removes excess cholesterol from cells and transports it to the liver for excretion or recycling.
Clarify the synthesis locations: LDL is synthesized in the liver, while HDL is synthesized in both the liver and intestines. This distinction is important for understanding their roles in lipid metabolism.
Explain their structural differences: LDL is primarily composed of lipids with a smaller proportion of proteins, making it less dense. HDL, on the other hand, has a higher proportion of proteins relative to lipids, giving it a higher density.
Relate their functions to cell signaling: LDL delivers cholesterol to cells, which is crucial for membrane synthesis and hormone production. HDL helps regulate cholesterol levels by removing excess cholesterol from cells, preventing cellular dysfunction and contributing to overall cardiovascular health.