A red blood cell will undergo hemolysis in which of the following solutions?

Relate the effect of each solution type on a red blood cell: In an isotonic solution, there is no net movement of water, so the cell remains unchanged. In a hypotonic solution, water moves into the cell, causing it to swell and potentially burst (hemolysis). In a hypertonic solution, water moves out of the cell, causing it to shrink.

Focus on the hypotonic solution: Since a hypotonic solution has a lower solute concentration than the cytoplasm, water will move into the red blood cell, increasing internal pressure and leading to hemolysis.