Here are the essential concepts you must grasp in order to answer the question correctly.
Antidiuretic Hormone (ADH)
Antidiuretic hormone (ADH), also known as vasopressin, is a hormone produced by the hypothalamus and released by the posterior pituitary gland. Its primary role is to regulate water balance in the body by controlling the amount of water reabsorbed by the kidneys. ADH increases the permeability of the kidney's collecting ducts to water, allowing more water to be reabsorbed back into the bloodstream, thus concentrating the urine and reducing urine volume.
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Nephron Structure
The nephron is the functional unit of the kidney, responsible for filtering blood and forming urine. It consists of several parts, including the glomerulus, proximal tubule, loop of Henle, distal tubule, and collecting duct. Each segment has specific functions in the process of urine formation, such as filtration, reabsorption, and secretion. Understanding the role of each part, particularly the collecting duct, is crucial for comprehending how ADH affects water reabsorption.
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Water Permeability in the Collecting Duct
Water permeability in the collecting duct is a key factor in the kidney's ability to concentrate urine. Under the influence of ADH, aquaporin channels are inserted into the membrane of the collecting duct cells, increasing their permeability to water. This allows more water to be reabsorbed from the filtrate back into the bloodstream, thereby concentrating the urine and conserving water in the body. This process is essential for maintaining fluid balance and preventing dehydration.
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