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Multiple Choice
Which event immediately precedes anaphase during mitosis?
A
Separation of sister chromatids
B
Alignment of chromosomes at the metaphase plate
C
Condensation of chromatin into visible chromosomes
D
Reformation of the nuclear envelope
Verified step by step guidance
1
Understand the sequence of events in mitosis: Mitosis is divided into several phases—prophase, metaphase, anaphase, and telophase. Each phase has specific events that occur in a precise order.
Focus on metaphase: During metaphase, chromosomes align at the metaphase plate, which is the central plane of the cell. This alignment ensures that sister chromatids are properly positioned for separation.
Identify the transition to anaphase: Anaphase begins when the sister chromatids are separated. This separation is facilitated by the shortening of spindle fibers attached to the kinetochores of the chromatids.
Determine the event immediately preceding anaphase: The alignment of chromosomes at the metaphase plate is the event that directly precedes anaphase. This alignment ensures that the chromatids are ready for separation.
Clarify the incorrect options: Condensation of chromatin into visible chromosomes occurs earlier in prophase, and reformation of the nuclear envelope happens later in telophase. These events are not directly related to the transition from metaphase to anaphase.