Multiple Choice
Which is the main event of transcription initiation?
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15. Gene Expression
Introduction to Transcription
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What is the function of general transcription factors (GTFs) in the initiation of transcription?
A
To synthesize RNA from a DNA template
B
To terminate transcription at the stop codon
C
To unwind the DNA double helix
D
To facilitate the binding of RNA polymerase to the promoter
Verified step by step guidance1
Understand that transcription is the process of synthesizing RNA from a DNA template, which involves several key steps and components.
Recognize that general transcription factors (GTFs) are proteins that play a crucial role in the initiation phase of transcription in eukaryotic cells.
Learn that the primary function of GTFs is to facilitate the binding of RNA polymerase II to the promoter region of a gene. The promoter is a specific DNA sequence that signals the start of a gene.
GTFs help in the formation of the transcription initiation complex by assembling at the promoter region, which allows RNA polymerase II to correctly position itself to begin RNA synthesis.
Note that while GTFs are essential for the initiation of transcription, they do not directly unwind the DNA double helix or terminate transcription. These functions are carried out by other proteins and mechanisms during the transcription process.
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