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Multiple Choice
Which of the following is an energy-requiring step of glycolysis?
A
Formation of pyruvate from phosphoenolpyruvate
B
Reduction of NAD+ to NADH
C
Conversion of 3-phosphoglycerate to 2-phosphoglycerate
D
Phosphorylation of glucose to glucose-6-phosphate
Verified step by step guidance
1
Understand that glycolysis is a metabolic pathway that converts glucose into pyruvate, releasing energy and producing ATP and NADH.
Identify the energy-requiring steps in glycolysis, which are typically the phosphorylation reactions that consume ATP.
Recall that the phosphorylation of glucose to glucose-6-phosphate is the first step in glycolysis and requires energy input in the form of ATP.
Recognize that this step involves the enzyme hexokinase, which catalyzes the transfer of a phosphate group from ATP to glucose, forming glucose-6-phosphate.
Note that this phosphorylation is crucial for trapping glucose within the cell and preparing it for further breakdown in glycolysis.