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Multiple Choice
Which statement correctly describes what causes the second voltage-gated Na$^+$ channel to open during an action potential?
A
The repolarization phase of the action potential opens the next Na$^+$ channel.
B
Depolarization of the membrane to the threshold potential triggers the opening of the next voltage-gated Na$^+$ channel.
C
A decrease in extracellular Na$^+$ concentration opens the next channel.
D
The binding of neurotransmitters directly to the Na$^+$ channel causes it to open.
Verified step by step guidance
1
Understand the context of the problem: The question is about the mechanism of action potentials in neurons, specifically how voltage-gated Na⁺ channels open sequentially during the propagation of an action potential.
Recall the key concept: Voltage-gated Na⁺ channels open in response to a change in membrane potential. This process is triggered by depolarization, which occurs when the inside of the neuron becomes less negative relative to the outside.
Identify the correct mechanism: Depolarization of the membrane to a specific threshold potential causes the voltage-gated Na⁺ channels to open. This is a key feature of the action potential propagation process.
Eliminate incorrect options: (1) Repolarization does not open Na⁺ channels; it closes them. (2) A decrease in extracellular Na⁺ concentration does not directly affect the opening of these channels. (3) Neurotransmitters bind to ligand-gated channels, not voltage-gated Na⁺ channels.
Conclude that the correct statement is: 'Depolarization of the membrane to the threshold potential triggers the opening of the next voltage-gated Na⁺ channel.' This is the mechanism by which the action potential propagates along the axon.