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Multiple Choice
How does the enzyme telomerase address the challenge of replicating the ends of linear chromosomes?
A
Telomerase removes damaged DNA from the ends of chromosomes.
B
Telomerase shortens the telomeres to prevent chromosome degradation.
C
Telomerase binds to the centromere to stabilize chromosome structure.
D
Telomerase adds repetitive nucleotide sequences to the ends of chromosomes.
Verified step by step guidance
1
Understand the challenge: During DNA replication, the enzymes responsible for copying DNA cannot fully replicate the very ends of linear chromosomes, known as telomeres. This can lead to the gradual shortening of chromosomes over successive cell divisions.
Recognize the role of telomerase: Telomerase is an enzyme that helps to maintain the length of telomeres, thus preventing the loss of important genetic information and ensuring chromosome stability.
Explore the mechanism: Telomerase adds repetitive nucleotide sequences to the ends of chromosomes. This process compensates for the inability of DNA polymerase to fully replicate the telomere regions.
Consider the structure of telomerase: Telomerase is a ribonucleoprotein, meaning it contains both protein and RNA components. The RNA component serves as a template for adding new DNA sequences to the telomeres.
Reflect on the biological significance: By maintaining telomere length, telomerase plays a crucial role in cellular aging and division. It is particularly active in stem cells and cancer cells, where it supports continuous cell division.