Here are the essential concepts you must grasp in order to answer the question correctly.
Galactosemia
Galactosemia is a genetic disorder where the body is unable to convert galactose into glucose due to the absence or malfunction of the enzyme galactose-1-phosphate uridylyltransferase. This leads to the accumulation of galactose in the blood, which can cause serious health issues such as liver damage, intellectual disability, and even death if not managed properly.
Enzyme Function
Enzymes are biological catalysts that speed up chemical reactions in the body. In the context of galactosemia, the enzyme galactose-1-phosphate uridylyltransferase is crucial for converting galactose into glucose. Without this enzyme, galactose accumulates, leading to toxic effects. Understanding enzyme function is essential for diagnosing and treating metabolic disorders like galactosemia.
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Dietary Sources of Galactose
Galactose is a sugar found in lactose, which is present in milk and dairy products. For individuals with galactosemia, it is critical to avoid foods containing lactose to prevent the accumulation of galactose. Physicians must advise patients to exclude lactose from their diet, as it directly contributes to the galactose levels in the body, exacerbating the condition.
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Sources of Genetic Variation