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Multiple Choice
Which of the following is a reason for post-transcriptional modification of mRNA in eukaryotic cells?
A
To promote protein degradation
B
To facilitate DNA replication
C
To increase mRNA stability
D
To enhance ribosomal RNA synthesis
Verified step by step guidance
1
Understand the concept of post-transcriptional modification: In eukaryotic cells, mRNA undergoes several modifications after transcription to become mature mRNA. These modifications are crucial for the stability and functionality of the mRNA.
Identify the types of post-transcriptional modifications: Common modifications include the addition of a 5' cap, polyadenylation at the 3' end, and splicing to remove introns. Each of these modifications serves specific purposes.
Explore the purpose of the 5' cap addition: The 5' cap is added to the mRNA to protect it from degradation and to assist in the initiation of translation. This increases the stability of the mRNA molecule.
Examine the role of polyadenylation: The addition of a poly-A tail at the 3' end of the mRNA also contributes to mRNA stability by protecting it from enzymatic degradation and aiding in the export of the mRNA from the nucleus.
Consider the impact of splicing: Splicing removes non-coding sequences (introns) from the mRNA, allowing the coding sequences (exons) to be properly expressed. This process is essential for producing a functional mRNA that can be translated into a protein.