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Multiple Choice
What did Sutherland discover about glycogen metabolism in liver cells?
A
Glucagon breaks down glycogen to glucose in liver cells.
B
The hormone that breaks down glycogen into glucose enters the liver cell.
C
Glucose is produced from glycogen when epinephrine binds to a cytoplasmic protein.
D
A cytoplasmic receptor triggers the signal transduction pathway that produces glucose from glycogen.
E
The hormone epinephrine binds to a specific receptor on the plasma membrane of the liver cell.
Verified step by step guidance
1
Understand the role of glycogen metabolism in liver cells: Glycogen is a stored form of glucose in the liver, and its breakdown is crucial for maintaining blood glucose levels.
Identify the hormones involved: Glucagon and epinephrine are key hormones that stimulate the breakdown of glycogen into glucose in liver cells.
Recognize the mechanism of action: Epinephrine binds to a specific receptor on the plasma membrane of liver cells, initiating a signal transduction pathway.
Explore the signal transduction pathway: The binding of epinephrine to its receptor activates a cascade of intracellular events, leading to the activation of enzymes that break down glycogen into glucose.
Conclude with Sutherland's discovery: Sutherland discovered that the hormone epinephrine binds to a specific receptor on the plasma membrane, triggering the breakdown of glycogen into glucose through a signal transduction pathway.