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Multiple Choice
Which of the following statements about incretin hormones is correct?
A
Incretin hormones inhibit glucose uptake in muscle cells.
B
Incretin hormones are primarily produced by pancreatic alpha cells.
C
Incretin hormones decrease the release of insulin after a meal.
D
Incretin hormones enhance insulin secretion in response to oral glucose intake.
Verified step by step guidance
1
Understand the role of incretin hormones: Incretin hormones are a group of metabolic hormones that stimulate insulin secretion in response to food intake, particularly oral glucose. They play a key role in glucose homeostasis.
Identify the primary source of incretin hormones: Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (gastric inhibitory polypeptide), are primarily produced by enteroendocrine cells in the small intestine, not pancreatic alpha cells.
Clarify the effect of incretin hormones on insulin: Incretin hormones enhance insulin secretion from pancreatic beta cells after a meal, especially when glucose is ingested orally. This is known as the incretin effect.
Address the incorrect statements: Incretin hormones do not inhibit glucose uptake in muscle cells; instead, they indirectly promote glucose uptake by enhancing insulin secretion. They also do not decrease insulin release; they increase it in response to oral glucose intake.
Conclude with the correct statement: The correct statement is that incretin hormones enhance insulin secretion in response to oral glucose intake, which helps regulate blood glucose levels after a meal.