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Multiple Choice
Which region of the lymph node contains follicles filled with dividing B cells?
A
Paracortex
B
Medulla
C
Hilum
D
Cortex
Verified step by step guidance
1
Understand the structure of a lymph node: A lymph node is divided into three main regions—cortex, paracortex, and medulla. Each region has distinct functions and cell populations.
Focus on the cortex: The cortex is the outermost region of the lymph node and contains lymphoid follicles. These follicles are specialized structures where B cells are activated and undergo division.
Learn about B cell activation: When B cells encounter antigens, they are activated in the follicles of the cortex. This leads to their proliferation and differentiation into plasma cells or memory B cells.
Differentiate the regions: The paracortex primarily contains T cells and dendritic cells, while the medulla contains macrophages and plasma cells. The hilum is the area where blood vessels and lymphatic vessels enter or exit the lymph node, not involved in B cell division.
Conclude that the cortex is the correct region: Based on the structure and function of the lymph node, the cortex is the region containing follicles filled with dividing B cells.