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Multiple Choice
During which phase of mitosis do spindle fibers first attach to kinetochores?
A
Metaphase
B
Prometaphase
C
Anaphase
D
Prophase
Verified step by step guidance
1
Understand the stages of mitosis: Mitosis is divided into several phases: prophase, prometaphase, metaphase, anaphase, and telophase.
Identify the role of spindle fibers: Spindle fibers are responsible for separating chromosomes during mitosis. They attach to kinetochores, which are protein structures on the chromosome.
Recognize the function of kinetochores: Kinetochores are crucial for chromosome movement and segregation. They serve as attachment points for spindle fibers.
Determine when spindle fibers attach to kinetochores: This attachment occurs during prometaphase, which is the phase following prophase and before metaphase.
Review the sequence of mitosis phases: In prometaphase, the nuclear envelope breaks down, allowing spindle fibers to access and attach to the kinetochores on the chromosomes.