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Multiple Choice
During which phase of mitosis do spindle fibers attach to the chromosomes at the centromere?
A
Metaphase
B
Telophase
C
Anaphase
D
Prophase
Verified step by step guidance
1
Understand the process of mitosis, which is divided into several phases: prophase, metaphase, anaphase, and telophase.
Recall that during prophase, the chromosomes condense and become visible, and the mitotic spindle begins to form, but the spindle fibers have not yet attached to the chromosomes.
In metaphase, the chromosomes align at the metaphase plate, and this is the phase where spindle fibers attach to the chromosomes at the centromere.
During anaphase, the spindle fibers shorten, pulling the sister chromatids apart toward opposite poles of the cell.
In telophase, the chromosomes reach the poles, and the nuclear envelope begins to reform around each set of chromosomes, marking the end of mitosis.