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Multiple Choice
What is the function of primase in DNA replication?
A
It unwinds the DNA double helix to allow replication to occur.
B
It synthesizes a short RNA primer to initiate DNA synthesis.
C
It joins Okazaki fragments on the lagging strand.
D
It adds nucleotides to the growing DNA strand in a 5' to 3' direction.
Verified step by step guidance
1
Understand the role of primase in DNA replication: Primase is an enzyme that plays a crucial role in the initiation of DNA synthesis.
Recognize the need for a primer: DNA polymerases, which synthesize DNA, cannot start the synthesis process on their own. They require a short RNA primer to begin adding nucleotides.
Learn how primase synthesizes the primer: Primase synthesizes a short RNA primer complementary to the DNA template strand, providing a starting point for DNA polymerase.
Identify the location of primer synthesis: Primase synthesizes the RNA primer at the origin of replication and at the start of each Okazaki fragment on the lagging strand.
Understand the importance of the primer: The RNA primer synthesized by primase is essential for DNA polymerase to begin DNA synthesis, ensuring accurate replication of the DNA molecule.