Understand the molecular structure and size of each molecule: Water (H₂O) is a small molecule with a simple structure. Glucose (C₆H₁₂O₆) is a monosaccharide, a simple sugar with a larger structure than water. Sucrose (C₁₂H₂₂O₁₁) is a disaccharide, composed of two monosaccharides, making it larger than glucose. Proteins are large, complex molecules made up of amino acids, significantly larger than the other molecules listed.