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Multiple Choice
Post-translational modifications of proteins can affect which of the following?
A
Protein function.
B
Protein location within the cell.
C
Protein activation or inactivation.
D
Protein degradation.
E
All of the above.
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Verified step by step guidance
1
Understand that post-translational modifications (PTMs) are chemical changes to a protein after it has been synthesized. These modifications can include phosphorylation, glycosylation, ubiquitination, and more.
Recognize that PTMs can alter protein function by changing its activity, stability, or interactions with other molecules. For example, phosphorylation can activate or deactivate enzymes.
Consider how PTMs can affect protein location within the cell. Some modifications serve as signals for proteins to be transported to specific cellular compartments.
Acknowledge that PTMs can regulate protein activation or inactivation. For instance, the addition of a phosphate group can switch a protein from an inactive to an active state.
Understand that PTMs can also target proteins for degradation. Ubiquitination is a common PTM that marks proteins for destruction by the proteasome.