Here are the essential concepts you must grasp in order to answer the question correctly.
Aquaporins
Aquaporins are specialized channel proteins embedded in cell membranes that facilitate the transport of water molecules. They play a crucial role in regulating water balance in the body, particularly in the kidneys, where they are essential for reabsorbing water from urine. The presence and quantity of aquaporins in cell membranes can be influenced by various hormones, including antidiuretic hormone (ADH).
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Antidiuretic Hormone (ADH)
Antidiuretic hormone (ADH), also known as vasopressin, is a hormone produced by the hypothalamus and released by the posterior pituitary gland. It regulates water retention in the body by promoting the insertion of aquaporins into the membranes of kidney collecting duct cells. Higher levels of ADH lead to increased water reabsorption, which is critical during dehydration, while lower levels result in less water being reabsorbed.
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Dehydration and Hydration
Dehydration occurs when the body loses more water than it takes in, leading to a higher concentration of solutes in the blood. In response, ADH levels increase, prompting the kidneys to insert more aquaporins into collecting duct cells, enhancing water reabsorption and concentrating urine. Conversely, during hydration, lower ADH levels result in fewer aquaporins, allowing more water to be excreted, thus diluting the urine and maintaining fluid balance.
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