Table of contents
- 1. Introduction to Biology2h 42m
- 2. Chemistry3h 37m
- 3. Water1h 26m
- 4. Biomolecules2h 23m
- 5. Cell Components2h 26m
- 6. The Membrane2h 31m
- 7. Energy and Metabolism2h 0m
- 8. Respiration2h 40m
- 9. Photosynthesis2h 49m
- 10. Cell Signaling59m
- 11. Cell Division2h 47m
- 12. Meiosis2h 0m
- 13. Mendelian Genetics4h 44m
- Introduction to Mendel's Experiments7m
- Genotype vs. Phenotype17m
- Punnett Squares13m
- Mendel's Experiments26m
- Mendel's Laws18m
- Monohybrid Crosses19m
- Test Crosses14m
- Dihybrid Crosses20m
- Punnett Square Probability26m
- Incomplete Dominance vs. Codominance20m
- Epistasis7m
- Non-Mendelian Genetics12m
- Pedigrees6m
- Autosomal Inheritance21m
- Sex-Linked Inheritance43m
- X-Inactivation9m
- 14. DNA Synthesis2h 27m
- 15. Gene Expression3h 6m
- 16. Regulation of Expression3h 31m
- Introduction to Regulation of Gene Expression13m
- Prokaryotic Gene Regulation via Operons27m
- The Lac Operon21m
- Glucose's Impact on Lac Operon25m
- The Trp Operon20m
- Review of the Lac Operon & Trp Operon11m
- Introduction to Eukaryotic Gene Regulation9m
- Eukaryotic Chromatin Modifications16m
- Eukaryotic Transcriptional Control22m
- Eukaryotic Post-Transcriptional Regulation28m
- Eukaryotic Post-Translational Regulation13m
- 17. Viruses37m
- 18. Biotechnology2h 58m
- 19. Genomics17m
- 20. Development1h 5m
- 21. Evolution3h 1m
- 22. Evolution of Populations3h 53m
- 23. Speciation1h 37m
- 24. History of Life on Earth2h 6m
- 25. Phylogeny2h 31m
- 26. Prokaryotes4h 59m
- 27. Protists1h 12m
- 28. Plants1h 22m
- 29. Fungi36m
- 30. Overview of Animals34m
- 31. Invertebrates1h 2m
- 32. Vertebrates50m
- 33. Plant Anatomy1h 3m
- 34. Vascular Plant Transport1h 2m
- 35. Soil37m
- 36. Plant Reproduction47m
- 37. Plant Sensation and Response1h 9m
- 38. Animal Form and Function1h 19m
- 39. Digestive System1h 10m
- 40. Circulatory System1h 49m
- 41. Immune System1h 12m
- 42. Osmoregulation and Excretion50m
- 43. Endocrine System1h 4m
- 44. Animal Reproduction1h 2m
- 45. Nervous System1h 55m
- 46. Sensory Systems46m
- 47. Muscle Systems23m
- 48. Ecology3h 11m
- Introduction to Ecology20m
- Biogeography14m
- Earth's Climate Patterns50m
- Introduction to Terrestrial Biomes10m
- Terrestrial Biomes: Near Equator13m
- Terrestrial Biomes: Temperate Regions10m
- Terrestrial Biomes: Northern Regions15m
- Introduction to Aquatic Biomes27m
- Freshwater Aquatic Biomes14m
- Marine Aquatic Biomes13m
- 49. Animal Behavior28m
- 50. Population Ecology3h 41m
- Introduction to Population Ecology28m
- Population Sampling Methods23m
- Life History12m
- Population Demography17m
- Factors Limiting Population Growth14m
- Introduction to Population Growth Models22m
- Linear Population Growth6m
- Exponential Population Growth29m
- Logistic Population Growth32m
- r/K Selection10m
- The Human Population22m
- 51. Community Ecology2h 46m
- Introduction to Community Ecology2m
- Introduction to Community Interactions9m
- Community Interactions: Competition (-/-)38m
- Community Interactions: Exploitation (+/-)23m
- Community Interactions: Mutualism (+/+) & Commensalism (+/0)9m
- Community Structure35m
- Community Dynamics26m
- Geographic Impact on Communities21m
- 52. Ecosystems2h 36m
- 53. Conservation Biology24m
8. Respiration
Fermentation & Anaerobic Respiration
Problem 6
Textbook Question
Which of the following is a distinction between cellular respiration and fermentation?
a. The transfer of from intermediate substrates to ADP
b. The movement of H+ across a membrane down its concentration gradient
c. The splitting of glucose into two molecules of pyruvate
d. Electrons moving through the electron transport chain

1
Step 1: Understand the key processes involved in cellular respiration and fermentation. Cellular respiration is an aerobic process (requires oxygen) that includes glycolysis, the citric acid cycle, and the electron transport chain. Fermentation, on the other hand, is an anaerobic process (does not require oxygen) and primarily involves glycolysis followed by the regeneration of NAD+ to allow glycolysis to continue.
Step 2: Analyze each option to determine if it applies to both cellular respiration and fermentation or only one of them. For example, consider whether the transfer of phosphate groups, movement of protons, splitting of glucose, or electron transport chain is unique to one process.
Step 3: Evaluate option (a): The transfer of phosphate groups from intermediate substrates to ADP (substrate-level phosphorylation) occurs in both cellular respiration and fermentation during glycolysis, so this is not a distinction.
Step 4: Evaluate option (b): The movement of H+ across a membrane down its concentration gradient is a feature of the electron transport chain in cellular respiration, but it does not occur in fermentation. This could be a distinction.
Step 5: Evaluate option (c) and (d): The splitting of glucose into two molecules of pyruvate (glycolysis) occurs in both processes, so it is not a distinction. Electrons moving through the electron transport chain is specific to cellular respiration and does not occur in fermentation, making it another possible distinction. Compare this with option (b) to determine the best answer.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Cellular Respiration
Cellular respiration is a metabolic process that converts glucose and oxygen into energy (ATP), carbon dioxide, and water. It occurs in three main stages: glycolysis, the citric acid cycle, and oxidative phosphorylation. This process is highly efficient and involves the electron transport chain, where electrons are transferred through a series of proteins, ultimately producing ATP through chemiosmosis.
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Fermentation
Fermentation is an anaerobic process that allows cells to generate energy without oxygen. It occurs after glycolysis when oxygen is not available, resulting in the conversion of pyruvate into lactic acid or ethanol and carbon dioxide. Fermentation produces less ATP compared to cellular respiration and does not involve the electron transport chain, making it a less efficient energy-producing pathway.
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Electron Transport Chain
The electron transport chain (ETC) is a series of protein complexes located in the inner mitochondrial membrane that facilitate the transfer of electrons derived from NADH and FADH2. As electrons move through the chain, they release energy used to pump protons (H+) across the membrane, creating a proton gradient. This gradient drives ATP synthesis via ATP synthase, a key feature of aerobic cellular respiration, distinguishing it from fermentation.
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Related Practice
Multiple Choice
Sports physiologists at an Olympic training center wanted to monitor athletes to determine at what point their muscles were functioning anaerobically. They could do this by checking for a buildup of which of the following compounds?
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