Multiple Choice
Taking one molecule of glucose through glycolysis, pyruvate oxidation, and the Krebs cycle generates:
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8. Respiration
Krebs Cycle
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Where do the reactions of the citric acid cycle occur in eukaryotic cells?
A
The cytosol
B
The cristae of the mitochondrion
C
The intermembrane space of the mitochondrion
D
Across the inner membrane of the mitochondrion
E
The matrix of the mitochondrion
Verified step by step guidance1
Understand the structure of a mitochondrion: It consists of an outer membrane, an inner membrane, and the space enclosed by the inner membrane called the matrix.
Recall the function of the citric acid cycle: It is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins.
Identify the location of the citric acid cycle: In eukaryotic cells, the citric acid cycle takes place in the mitochondrial matrix, where the necessary enzymes and substrates are located.
Differentiate between the mitochondrial compartments: The matrix is distinct from the intermembrane space, the cristae (folds of the inner membrane), and the inner membrane itself, which are involved in other processes like oxidative phosphorylation.
Conclude that the correct location for the citric acid cycle in eukaryotic cells is the matrix of the mitochondrion, where the cycle's enzymes are found and where the reactions occur.
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