Negative & Positive Feedback quiz #1 Flashcards
Negative & Positive Feedback quiz #1
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What is negative feedback in a metabolic pathway?
Negative feedback is when the final product of a metabolic pathway inhibits an earlier step in the same pathway, slowing or stopping further production. How does negative feedback regulate metabolic pathways?
Negative feedback regulates metabolic pathways by inhibiting an enzyme in an earlier step, which decreases the production of the final product. What is the role of the final product in negative feedback?
In negative feedback, the final product acts as an inhibitor to an enzyme earlier in the pathway, reducing its own further synthesis. How is negative feedback similar to a red light in traffic?
Negative feedback is like a red light because it signals the pathway to stop or slow down, preventing overproduction of the final product. What is positive feedback in a metabolic pathway?
Positive feedback is when the final product of a metabolic pathway stimulates an earlier step in the same pathway, increasing production. How does positive feedback affect enzyme activity in a pathway?
Positive feedback increases the activity of an enzyme in an earlier step, leading to more production of the final product. What is the effect of positive feedback on the production of the final product?
Positive feedback accelerates the pathway, resulting in increased synthesis of the final product. How is positive feedback similar to a green light in traffic?
Positive feedback is like a green light because it signals the pathway to go faster, promoting more production of the final product. Why is negative feedback important for homeostasis?
Negative feedback helps maintain homeostasis by preventing the overaccumulation of metabolic products. In negative feedback, which step is typically inhibited?
An earlier step, often the first enzyme in the pathway, is typically inhibited by the final product. What happens if negative feedback is disrupted in a cell?
If negative feedback is disrupted, the cell may overproduce the final product, potentially leading to imbalance or toxicity. When might a cell use positive feedback in metabolism?
A cell might use positive feedback when it needs to rapidly increase the production of a specific metabolic product. What is the main difference between negative and positive feedback in metabolic regulation?
Negative feedback inhibits earlier steps to decrease product formation, while positive feedback stimulates earlier steps to increase product formation. How does the final product interact with enzymes in positive feedback?
In positive feedback, the final product stimulates an enzyme in an earlier step, enhancing its activity. What is the biological significance of feedback mechanisms in metabolism?
Feedback mechanisms allow cells to regulate metabolic pathways efficiently, adapting to changing needs and maintaining balance. Can both negative and positive feedback occur in the same metabolic pathway?
Yes, both types of feedback can occur, but usually at different times or under different conditions to regulate production as needed. What symbol is commonly used to represent inhibition in feedback diagrams?
A negative sign (−) is commonly used to represent inhibition in feedback diagrams. What symbol is commonly used to represent stimulation in feedback diagrams?
A positive sign (+) is commonly used to represent stimulation in feedback diagrams. How does negative feedback contribute to metabolic efficiency?
Negative feedback prevents wasteful overproduction of products, conserving energy and resources. What would happen if positive feedback continued unchecked in a metabolic pathway?
Unchecked positive feedback could lead to excessive accumulation of the final product, potentially disrupting cellular function. Why is it important for cells to limit the production of certain metabolic products?
Limiting production prevents resource waste, toxicity, and maintains cellular balance. How does feedback regulation relate to enzyme activity?
Feedback regulation alters enzyme activity, either inhibiting or stimulating it to control the pathway's output. What is an example of a molecule that could act as a feedback inhibitor?
The final product of a metabolic pathway, such as molecule F, can act as a feedback inhibitor. How does feedback inhibition differ from competitive inhibition?
Feedback inhibition involves the final product inhibiting an earlier enzyme in the same pathway, while competitive inhibition involves a molecule competing with the substrate for the enzyme's active site. What is the overall purpose of feedback mechanisms in metabolic pathways?
The purpose is to regulate the amount of final product produced, ensuring cellular needs are met without excess. How do feedback mechanisms help maintain homeostasis in biological systems?
Feedback mechanisms adjust metabolic activity to keep internal conditions stable, supporting homeostasis.