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Ch. 24 The Immune System
Taylor - Campbell Biology: Concepts & Connections 10th Edition
Taylor, Simon, Dickey, Hogan10th EditionCampbell Biology: Concepts & ConnectionsISBN: 9780136538783Not the one you use?Change textbook
Chapter 24, Problem 15

Organ donation saves many lives each year. Even though some transplanted organs are derived from living donors, the majority come from patients who die but still have healthy organs that can be of value to a transplant recipient. Potential organ donors can fill out an organ donation card to specify their wishes. If the donor is in critical condition and dying, the donor's family is usually consulted to discuss the donation process. Generally, the next of kin must approve before donation can occur, regardless of whether the patient has completed an organ donation card. In some cases, a family member overrides the donor's wishes. Do you think that family members should be able to overrule the stated intentions of the potential donor? Why or why not? Have you signed up to be an organ donor? Why or why not?

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Identify the ethical considerations involved in organ donation, particularly focusing on the autonomy of the donor versus the feelings and rights of the family members.
Examine the legal framework surrounding organ donation in your region or country, which might influence whether family members have the right to override the donor's wishes.
Consider the potential consequences of allowing family members to override the donor's wishes, both in terms of the availability of organs for transplantation and the respect for the donor's autonomy.
Reflect on the emotional and psychological impact on the family members who might be in a state of grief and may not be in the best position to make such decisions.
Evaluate your personal stance on organ donation and how it aligns with your values and beliefs about autonomy, medical ethics, and the importance of organ donation in saving lives.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Organ Donation Process

The organ donation process involves the retrieval of organs from donors, which can be either living or deceased. In cases of deceased donors, organs are typically harvested after brain death is confirmed, while living donors can donate specific organs like a kidney. The process requires careful medical evaluation to ensure the organs are healthy and suitable for transplantation, and it often involves legal and ethical considerations regarding consent.
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Informed Consent

Informed consent is a fundamental principle in medical ethics that requires individuals to be fully informed about the implications of their decisions regarding medical procedures, including organ donation. This means that potential donors should understand the risks, benefits, and alternatives before agreeing to donate. In the context of organ donation, it also encompasses the idea that family members may have a say in the decision, which can complicate the donor's previously expressed wishes.
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Ethical Considerations in Organ Donation

Ethical considerations in organ donation revolve around the rights of the donor, the wishes of the family, and the societal need for organs. This includes debates on whether family members should have the authority to override a donor's wishes, balancing respect for individual autonomy against the emotional and moral implications for the family. These discussions often reflect broader societal values regarding life, death, and the responsibilities of individuals towards their loved ones.
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Related Practice
Textbook Question

Pertussis (whooping cough) is caused by a bacterial infection, and symptoms include an intense cough that lasts for weeks, sometimes leading to pneumonia and death. A complete vaccination against pertussis requires five doses, completed by age 5. A pertussis outbreak occurred in California in 2010, and a news article reported the following: 'Among fully immunized kids, there were about 36 cases for every 10,000 children two to seven years old, compared to 245 out of every 10,000 kids aged eight to twelve.' Propose an explanation for these data and a public health solution based on your explanation.

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Textbook Question
Your roommate is rushed to the hospital after suffering a severe allergic reaction to a bee sting. After she is treated and released, she asks you (the local biology expert!) to explain what happened. She says, 'I don't understand how this could have happened. I've been stung by bees before and didn't have a reaction.' Suggest an explanation for what has happened to cause her severe allergic reaction and why she did not have the reaction after previous bee stings.
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Textbook Question

Compare the outcomes of two different cases of infectious diseases in a community.

Case 1: A man with an infectious disease enters a community where the disease has not previously occurred.

Case 2: A man with an infectious disease enters a community where almost everyone has been vaccinated against the disease.

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Textbook Question
One of the key difficulties in the development of anti-HIV drugs is the fact that HIV only infects humans. This precludes the testing of drugs in animals and instead requires that drugs be tested on volunteer human subjects. The developing world (particularly sub-Saharan Africa and Southeast Asia) has the highest rates of HIV infection. Consequently, drug companies frequently conduct studies in these regions. Some people decry such tests, fearing that drug companies may profit hugely from the use of economically disadvantaged people. Others counter that such tests are the only way to find new and cheaper drugs that will ultimately help everyone. What do you think are the ethical issues surrounding trials of anti-HIV drugs in the developing world? Which side do you think has the more morally compelling argument?
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