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Multiple Choice
In adult human hematopoiesis, mature red blood cells (erythrocytes) are ultimately derived from which cell type?
A
Hematopoietic stem cell (HSC) in the bone marrow
B
Mesenchymal stem cell (MSC) in the bone marrow stroma
C
Neural stem cell from the subventricular zone
D
Satellite cell (skeletal muscle stem cell)
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Verified step by step guidance
1
Understand the process of hematopoiesis, which is the formation of blood cellular components, including red blood cells (erythrocytes).
Identify the origin of all blood cells in adults, which is the bone marrow, where specialized stem cells reside.
Recognize that hematopoietic stem cells (HSCs) are multipotent stem cells in the bone marrow responsible for giving rise to all mature blood cells, including erythrocytes.
Differentiate hematopoietic stem cells from other stem cell types such as mesenchymal stem cells (which give rise to bone, cartilage, and fat cells), neural stem cells (which generate neural tissue), and satellite cells (which are muscle stem cells).
Conclude that mature red blood cells are ultimately derived from hematopoietic stem cells (HSCs) located in the bone marrow.