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Multiple Choice
In the context of gene expression control, a cell described as having an upregulated gene most directly has an increase in which of the following?
A
The number of chromosomes in the nucleus
B
The rate of DNA replication at that gene's locus
C
The frequency of random point mutations in that gene
D
Transcription of that gene, leading to higher levels of its mRNA
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Verified step by step guidance
1
Understand the term 'upregulated gene' in gene expression: it means the gene's activity is increased, resulting in more gene product being made.
Recall that gene expression involves multiple stages: transcription (DNA to mRNA) and translation (mRNA to protein). Upregulation typically refers to increased transcription.
Evaluate the options given: an increase in chromosome number or DNA replication rate does not directly indicate gene upregulation; similarly, mutation frequency is unrelated to expression levels.
Focus on transcription, which is the process where the DNA sequence of a gene is copied into mRNA. Upregulation means this process happens more frequently or efficiently for that gene.
Conclude that an upregulated gene most directly shows an increase in the transcription of that gene, leading to higher mRNA levels.