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Multiple Choice
In mitosis, what best describes metaphase?
A
The nuclear envelope re-forms around each set of chromosomes and chromosomes begin to decondense.
B
Chromosomes align at the cell’s equatorial plane (metaphase plate) with spindle microtubules attached to kinetochores.
C
DNA is replicated to produce identical sister chromatids.
D
Sister chromatids separate and move toward opposite poles of the cell.
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Verified step by step guidance
1
Understand that mitosis is divided into distinct phases: prophase, metaphase, anaphase, and telophase, each with specific events.
Recall that during metaphase, chromosomes are highly condensed and align in the center of the cell, specifically at the equatorial plane, also called the metaphase plate.
Recognize that spindle microtubules attach to the kinetochores of each chromosome, which are protein structures on the centromere, to prepare for separation.
Note that the nuclear envelope does not re-form during metaphase; this occurs later in telophase.
Distinguish metaphase from other phases by remembering that DNA replication happens before mitosis (in S phase), and sister chromatids separate during anaphase, not metaphase.