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Multiple Choice
During metaphase of mitosis, which of the following events occurs?
A
The nuclear envelope reforms around each set of chromosomes and the mitotic spindle disassembles.
B
Chromatin condenses into visible chromosomes and the mitotic spindle begins to form as centrosomes move apart.
C
Sister chromatids separate and move toward opposite poles of the cell.
D
Chromosomes align at the cell's equatorial plane (metaphase plate) with sister chromatids attached to spindle microtubules from opposite poles.
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1
Understand the stages of mitosis and the key events that characterize each phase: prophase, metaphase, anaphase, and telophase.
Recall that during metaphase, chromosomes become highly condensed and align at the cell's equatorial plane, known as the metaphase plate.
Recognize that sister chromatids are attached to spindle microtubules originating from opposite centrosomes (poles) to ensure proper segregation.
Differentiate metaphase from other phases: prophase involves chromatin condensation and spindle formation; anaphase involves separation of sister chromatids; telophase involves nuclear envelope reformation and spindle disassembly.
Conclude that the defining event of metaphase is the alignment of chromosomes at the metaphase plate with sister chromatids attached to spindle fibers from opposite poles.