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Multiple Choice
During anaphase of mitosis, what structure directly generates the force that moves sister chromatids toward opposite spindle poles?
A
Expansion of the endoplasmic reticulum that physically pushes chromatids apart
B
Intermediate filaments (lamins) contracting to drag chromatids to the poles
C
Shortening (depolymerization) of kinetochore microtubules in the mitotic spindle
D
Thick filaments of myosin II pulling chromatids along actin stress fibers
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Verified step by step guidance
1
Understand the context: During anaphase of mitosis, sister chromatids are separated and moved toward opposite spindle poles to ensure each daughter cell receives an identical set of chromosomes.
Identify the cellular structures involved in chromosome movement: The mitotic spindle, composed mainly of microtubules, plays a critical role in this process.
Recall the role of kinetochore microtubules: These microtubules attach to the kinetochores on chromatids and are responsible for pulling chromatids apart.
Recognize the mechanism generating force: The shortening or depolymerization of kinetochore microtubules at their plus ends near the kinetochores generates the pulling force that moves chromatids toward the poles.
Eliminate incorrect options: Expansion of the endoplasmic reticulum, contraction of intermediate filaments (lamins), and myosin II pulling along actin stress fibers are not involved in the direct movement of chromatids during anaphase.