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Multiple Choice
In mitosis, during which phase does the nuclear envelope break down so that the nucleus is no longer visible as a distinct structure?
A
Telophase
B
Metaphase
C
Prophase (often specified as prometaphase in detailed descriptions)
D
Anaphase
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Verified step by step guidance
1
Recall the stages of mitosis: prophase, prometaphase, metaphase, anaphase, and telophase.
Understand that the nuclear envelope is intact during early prophase, allowing the nucleus to be visible as a distinct structure.
Identify that the nuclear envelope begins to break down during prometaphase, which is often considered part of late prophase or a separate phase.
Recognize that once the nuclear envelope breaks down, the chromosomes are no longer enclosed within the nucleus and become accessible to spindle fibers.
Conclude that the phase during which the nuclear envelope breaks down and the nucleus is no longer visible as a distinct structure is prophase, specifically prometaphase.