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Multiple Choice
Where does glycolysis primarily occur in a eukaryotic cell?
A
Inner mitochondrial membrane
B
Nucleus
C
Mitochondrial matrix
D
Cytosol (cytoplasm)
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Verified step by step guidance
1
Recall the main cellular compartments involved in metabolism within a eukaryotic cell: the cytosol (cytoplasm), mitochondria (including the matrix and inner membrane), and the nucleus.
Understand that glycolysis is the metabolic pathway that breaks down glucose into pyruvate, producing ATP and NADH in the process.
Identify that glycolysis does not require mitochondria and occurs independently of oxygen availability, which suggests it takes place outside the mitochondria.
Recognize that the cytosol (cytoplasm) is the fluid portion of the cell outside organelles where many enzymatic reactions occur, including glycolysis.
Conclude that glycolysis primarily occurs in the cytosol (cytoplasm) of eukaryotic cells, not in the mitochondrial matrix, inner mitochondrial membrane, or nucleus.