Multiple Choice
Ribosomes are synthesized in which of the following locations?
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5. DNA to RNA to Protein
mRNA Export and Nuclear Structures
Multiple Choice
In the context of mRNA export and nuclear structures, which statement best describes whether DNA can leave the nucleus in a typical eukaryotic cell?
A
DNA is exported from the nucleus only after it binds to ribosomes, which facilitate its passage through the nuclear lamina.
B
DNA leaves the nucleus during interphase by vesicular transport from the inner nuclear membrane to the cytosol.
C
DNA generally does not leave the nucleus; instead, RNA (such as mRNA) is exported to the cytoplasm through nuclear pore complexes.
D
DNA routinely exits the nucleus through nuclear pore complexes to be translated by ribosomes in the cytoplasm.
Verified step by step guidance1
Understand the basic organization of genetic material in eukaryotic cells: DNA is housed within the nucleus, where it serves as the template for RNA synthesis.
Recall that the nuclear envelope separates the nucleus from the cytoplasm and contains nuclear pore complexes (NPCs) that regulate molecular traffic between these compartments.
Recognize that DNA is a large, double-stranded molecule tightly packed into chromatin and is generally too large and structurally constrained to pass through NPCs.
Know that instead of DNA leaving the nucleus, messenger RNA (mRNA) is synthesized from DNA and then exported through NPCs to the cytoplasm, where ribosomes translate the mRNA into proteins.
Conclude that DNA does not leave the nucleus under normal conditions; the correct statement is that RNA, not DNA, is exported to the cytoplasm via nuclear pore complexes.
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