Multiple Choice
Elongation factors get the energy to elongate the polypeptide chain through which of the following processes?
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5. DNA to RNA to Protein
Translation
Multiple Choice
During translation initiation, the initiator tRNA first binds to the ribosome's _____ site.
A
mRNA exit channel
B
P site
C
E site
D
A site
Verified step by step guidance1
Understand the structure of the ribosome during translation initiation, which has three key sites for tRNA binding: the A (aminoacyl) site, the P (peptidyl) site, and the E (exit) site.
Recall that during translation initiation, the initiator tRNA carrying the first amino acid (usually methionine in eukaryotes) must be positioned correctly to start polypeptide synthesis.
Recognize that the initiator tRNA binds directly to the P site of the ribosome, where the growing polypeptide chain is held during elongation.
Note that the A site is where incoming aminoacyl-tRNAs bind during elongation, and the E site is where tRNAs exit after donating their amino acid.
Therefore, the correct site for the initiator tRNA binding during translation initiation is the P site.
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