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Multiple Choice
During meiosis I (often contrasted with mitosis), what separates during anaphase I after alignment at metaphase I?
A
The nuclear envelope separates into two identical nuclei before chromosome movement begins.
B
Centrioles separate from each other but chromosomes remain paired at the metaphase plate.
C
Sister chromatids separate at the centromeres.
D
Homologous chromosomes separate while sister chromatids remain together.
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Verified step by step guidance
1
Recall the key difference between meiosis I and mitosis during anaphase: in meiosis I, homologous chromosomes separate, whereas in mitosis, sister chromatids separate.
Understand that during metaphase I of meiosis, homologous chromosome pairs (each consisting of two sister chromatids) align at the metaphase plate.
During anaphase I, the homologous chromosomes are pulled apart to opposite poles of the cell, but the sister chromatids remain attached at their centromeres.
Note that the nuclear envelope does not separate into two nuclei before chromosome movement; this occurs later during telophase.
Recognize that centrioles do separate to help form spindle fibers, but the critical event defining anaphase I is the separation of homologous chromosomes, not sister chromatids.