Multiple Choice
Which of the following is not a protein coat?
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13. Intracellular Protein Transport
Vesicular Budding, Transport, and Coat Proteins
Multiple Choice
In the context of vesicular budding, transport, and coat proteins, what is the primary mechanism that transports newly synthesized proteins between organelles such as the ER and Golgi within the cell?
A
Ribosomes moving along microtubules while carrying completed proteins to their destinations
B
Direct transfer of proteins through gap junctions between adjacent cells
C
Free diffusion of proteins through the cytosol without membrane carriers
D
Coated transport vesicles that bud from a donor membrane and fuse with a target membrane
Verified step by step guidance1
Understand that newly synthesized proteins are transported between organelles such as the ER and Golgi via vesicular transport, which involves membrane-bound carriers rather than free diffusion or direct cell-to-cell transfer.
Recognize that coat proteins (such as COPI, COPII, and clathrin) play a crucial role in vesicular budding by shaping the membrane and selecting cargo proteins for transport.
Identify that the process begins with the budding of a coated vesicle from the donor membrane (e.g., ER), which encloses the cargo proteins destined for the target organelle (e.g., Golgi).
Know that after budding, the vesicle sheds its coat proteins and is guided to the target membrane, where it docks and fuses, delivering the cargo proteins into the target organelle.
Conclude that this mechanism—coated transport vesicles budding from donor membranes and fusing with target membranes—is the primary way cells transport newly synthesized proteins between organelles.
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