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Multiple Choice
In eukaryotic cells, the majority of ATP is produced by oxidative phosphorylation at which mitochondrial location?
A
Inner mitochondrial membrane (cristae), where ATP synthase is embedded
B
Intermembrane space as the primary site of ATP generation
C
Outer mitochondrial membrane
D
Mitochondrial matrix as free soluble ATP synthase
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Verified step by step guidance
1
Understand the process of oxidative phosphorylation, which is the main method by which eukaryotic cells produce ATP during cellular respiration.
Recall that oxidative phosphorylation involves the electron transport chain (ETC) and ATP synthase working together to generate ATP.
Identify the location of the electron transport chain complexes and ATP synthase within the mitochondrion; these are embedded in the inner mitochondrial membrane, specifically in the folds called cristae.
Recognize that the intermembrane space is important for creating a proton gradient but is not the site where ATP synthase is located or where ATP is directly produced.
Conclude that the inner mitochondrial membrane (cristae) is the correct location for ATP production by oxidative phosphorylation, as ATP synthase is embedded there and uses the proton gradient to synthesize ATP.