Multiple Choice
In B cell development, which differentiated cell type is primarily responsible for producing and secreting large amounts of antibodies?
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21. The Immune System
B Cell Development
Multiple Choice
In the context of B cell development and adaptive immunity, which cell type is primarily responsible for humoral immunity (antibody-mediated immunity)?
A
B lymphocytes (B cells), which can differentiate into antibody-secreting plasma cells
B
Natural killer (NK) cells, which lyse cells with low MHC class I expression
C
CD8+ cytotoxic T lymphocytes, which directly kill virus-infected cells
D
Neutrophils, which provide rapid phagocytic defense in innate immunity
Verified step by step guidance1
Understand the concept of humoral immunity, which refers to the aspect of adaptive immunity that involves the production of antibodies to neutralize pathogens.
Recall that B lymphocytes (B cells) are the primary cells responsible for humoral immunity because they can differentiate into plasma cells that secrete antibodies.
Recognize that other cell types listed, such as natural killer (NK) cells, CD8+ cytotoxic T lymphocytes, and neutrophils, have different roles: NK cells and CD8+ T cells are involved in cell-mediated immunity, while neutrophils are part of innate immunity.
Identify that the key function of B cells in humoral immunity is their ability to produce specific antibodies that target extracellular pathogens and toxins.
Conclude that among the options, B lymphocytes are the correct cell type responsible for antibody-mediated (humoral) immunity.
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