Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

12. Gene Regulation in Prokaryotes

Lac Operon

Genetics

12. Gene Regulation in Prokaryotes

Lac Operon

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Multiple Choice

Glucose concentration can regulate the lac operon?

True

False

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Verified step by step guidance

Understand the lac operon: The lac operon is a set of genes in bacteria that are involved in the metabolism of lactose. It is regulated by the presence or absence of lactose and glucose in the environment.

Identify the role of glucose: In the presence of glucose, bacteria prefer to use glucose over lactose because it is a more efficient energy source. This preference affects the regulation of the lac operon.

Explore catabolite repression: When glucose is present, it inhibits the activation of the lac operon through a mechanism called catabolite repression. This involves the reduction of cyclic AMP (cAMP) levels, which are necessary for the activation of the lac operon.

Examine the role of cAMP and CAP: cAMP binds to the catabolite activator protein (CAP), and this complex is required for the transcription of the lac operon. In the presence of glucose, cAMP levels drop, reducing the binding of the cAMP-CAP complex to the lac operon promoter, thus inhibiting its expression.

Conclude the relationship: Since glucose concentration affects the levels of cAMP and subsequently the activity of the lac operon, it is true that glucose concentration can regulate the lac operon.