Textbook Question
When a codon in an mRNA with the sequence 5'-UAA-3' enters the A site of a ribosome, it is not recognized by a tRNA with a complementary anticodon. Why not? What recognizes it instead?
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11. Translation
Translation
2:35 minutesProblem 15a
Textbook Question
The three major forms of RNA (mRNA, tRNA, and rRNA) interact during translation.
Describe the role each form of RNA performs during translation.
Verified step by step guidance1
Understand that translation is the process by which the genetic code in mRNA is used to synthesize a protein. This process occurs in the ribosome and involves three major forms of RNA: mRNA, tRNA, and rRNA.
mRNA (messenger RNA) serves as the template for translation. It carries the genetic code from DNA in the form of codons, which are sequences of three nucleotides that specify particular amino acids.
tRNA (transfer RNA) acts as the adapter molecule. Each tRNA has an anticodon region that pairs with a complementary codon on the mRNA and a specific amino acid attachment site. This ensures that the correct amino acid is added to the growing polypeptide chain.
rRNA (ribosomal RNA) is a structural and functional component of the ribosome. It helps catalyze the formation of peptide bonds between amino acids and ensures proper alignment of the mRNA and tRNA during translation.
Combine the roles: mRNA provides the instructions, tRNA brings the correct amino acids, and rRNA facilitates the assembly of the protein. Together, these RNAs coordinate to translate the genetic code into a functional protein.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
mRNA (messenger RNA)
mRNA is a type of RNA that carries genetic information from DNA to the ribosome, where proteins are synthesized. It is transcribed from a gene and serves as a template for the sequence of amino acids in a protein. During translation, the ribosome reads the mRNA sequence in sets of three nucleotides, known as codons, to assemble the corresponding amino acids.
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tRNA (transfer RNA)
tRNA is responsible for bringing the appropriate amino acids to the ribosome during translation. Each tRNA molecule has an anticodon that is complementary to a specific mRNA codon, ensuring that the correct amino acid is added to the growing polypeptide chain. This process is crucial for accurately translating the genetic code into functional proteins.
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rRNA (ribosomal RNA)
rRNA is a structural and functional component of ribosomes, the cellular machinery that facilitates protein synthesis. It helps to stabilize the binding of mRNA and tRNA during translation and catalyzes the formation of peptide bonds between amino acids. rRNA plays a critical role in ensuring the efficiency and accuracy of the translation process.
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