Here are the essential concepts you must grasp in order to answer the question correctly.
Chromosome Number and Karyotype
A karyotype is a visual representation of an organism's complete set of chromosomes, organized by size and shape. In this case, the male donkey has 62 chromosomes (2n=62) and the female horse has 64 chromosomes (2n=64). Mules, which are hybrids of these two species, typically have 63 chromosomes (2n=63), resulting from the combination of one set from each parent.
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Hybrid Sterility
Hybrid sterility occurs when the offspring of two different species are unable to reproduce. In the case of mules, they are sterile because they have an odd number of chromosomes (63), which complicates meiosis—the process of forming gametes. During meiosis, the chromosomes cannot pair properly, leading to the production of nonviable gametes.
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Meiosis and Gamete Formation
Meiosis is a specialized type of cell division that reduces the chromosome number by half, producing gametes (sperm and eggs). In sexually reproducing organisms, proper pairing and segregation of homologous chromosomes are crucial for viable gamete formation. In mules, the lack of homologous pairs due to the odd chromosome number disrupts this process, resulting in infertility.
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