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1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

6. Chromosomal Variation

Chromosomal Mutations: Aneuploidy

Genetics

6. Chromosomal Variation

Chromosomal Mutations: Aneuploidy

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Multiple Choice

Which of the following is a way in which monosomy can occur?

Duplication of a chromosome segment

Translocation of a chromosome segment to another chromosome

Polyploidy resulting from whole genome duplication

Nondisjunction during meiosis leading to the loss of a chromosome

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Verified step by step guidance

Understand the definition of monosomy: it is a condition where an organism has only one copy of a particular chromosome instead of the usual two.

Review the mechanisms listed and consider how each affects chromosome number or structure:

- Duplication of a chromosome segment increases the amount of genetic material but does not reduce chromosome number, so it does not cause monosomy.

- Translocation involves the movement of a chromosome segment to another chromosome, which changes chromosome structure but typically does not result in the loss of an entire chromosome.

- Polyploidy involves the duplication of the entire genome, increasing chromosome sets rather than causing loss, so it does not cause monosomy.

Recognize that nondisjunction during meiosis can lead to the failure of chromosomes to separate properly, resulting in gametes missing a chromosome, which upon fertilization leads to monosomy.