Radiotherapy (treatment with ionizing radiation) is one of the most effective current cancer treatments. It works by damaging DNA and other cellular components. In which ways could radiotherapy control or cure cancer, and why does radiotherapy often have significant side effects?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
19. Cancer Genetics
Overview of Cancer
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Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
Which of the following best describes a proto-oncogene in the context of cancer genetics?
A
A gene that repairs DNA damage and prevents mutations
B
A mutated gene that directly causes uncontrolled cell division
C
A gene that triggers programmed cell death (apoptosis)
D
A normal gene that can become an oncogene due to mutations or increased expression

1
Understand the role of proto-oncogenes in normal cell biology: Proto-oncogenes are normal genes that regulate cell growth and division under controlled conditions.
Recognize that when proto-oncogenes undergo mutations or are overexpressed, they can become oncogenes, which may lead to uncontrolled cell proliferation and contribute to cancer development.
Differentiate proto-oncogenes from tumor suppressor genes, which normally function to repair DNA or induce apoptosis to prevent cancer.
Identify that a proto-oncogene itself is not mutated or harmful, but its altered form (oncogene) is associated with cancer.
Conclude that the best description of a proto-oncogene is a normal gene that can become an oncogene due to mutations or increased expression.
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